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St. Denis Medical Season 2 premiered on NBC on November 3, 2025, and has dropped five episodes so far. There have been a few developments, and we have recently seen Alex realise why her mentor wasn't the best person, and how Serena and Matt might just become a couple if things go well.
The next episode of the show, I Left a Woman on the Table, will be released on NBC on December 1, 2025. You'll also be able to stream if on Peacock the next day.
St. Denis Medical Season 2 Episode 6
St. Denis Medical Season 2 is set a few months after the end of Season 1. At the beginning of the new season, we see Alex coming back from her trip to Hawaii which means she did finally take a break from work. She then intended to hold onto her relaxed mindset at the hospital, but ends up dealing with a tough moment with Ron.
Serena discovered that Matt asked to be reassigned just so he wouldn’t have to be around her, and when confronted, he explained that the distance was necessary and helped him move past his feelings.
A lot has happened since then, and In the latest episode, A Strong Cup of Coffee, we saw how Alex's mentor Pam visiting wasn't really the best thing for the hospital as Alex had thought it would be. Serena also might deal with her feelings for Matt, and their relationship might develop in the next episode.
St. Denis Medical Season 2 Episode 6, I Left a Woman on the Table will be released on NBC on December 1, 2025, Monday, at 8 pm ET. In case you miss it on the day of release, you can stream it on Peacock the next day. To do so, you will need to be subscribed to Peacock. You can either subscribe to Peacock Premium which will cost you $10.99 per month or $109.99 annually and comes with ads or the Peacock Premium Plus plan, which is ad-free and will cost you $16.99 per month ir $169.99 annually.
St. Denis Medical Season 2 stars Wendi McLendon-Covey as Joyce, Allison Tolman as Alex, Josh Lawson as Bruce, Kahyun Kim as Serena, Mekki Leeper as Matt, David Alan Grier as Ron, Kaliko Kauahi as Val, Kyle Bornheimer as Tim, Draymond Green as Lightning Patient, and Ariana Madix as Dr. Emerson, among others.
The show is created by Eric Ledgin and Justin Spitzer, who also executive produce the show along with Simon Heuer, Ruben Fleischer, Bridget Kyle, and Vicky Luu. Meg Schave has produced the show. The production companies behind the show are More Bees, Inc., Spitzer Holding Company, and Universal Television.
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